What Is Phosphatidylserine?
Phosphatidylserine (PS) is a phospholipid that contains both amino acids and fatty acids. The omega-3 fatty acids EPA and DHA work synergistically with PS to provide the building blocks for healthy cell membranes. The human body can make phosphatidylserine, but it obtains most of what it requires from foods.
Phospholipids, which surround all of our cells, are essential molecules that provide cellular structure and protection. A phospholipid molecule is constructed from four components: fatty acids, a platform to which the fatty acids are attached, phosphate and alcohol attached to the phosphate.
Phospholipids line up and arrange themselves into two parallel layers known as a phospholipid bilayer. This is the layer that makes up your cell membranes and is critical to each of your cell’s ability to function.
Phosphatidylserine is critical to the maintenance of all cellular function, especially in the brain. Research also shows that it’s important to:
- Bone matrix formation
- Cell repair and removal by the immune system
- Heartbeat coordination
- Hormone secretion by the adrenal glands
- Testicular function
Health Benefits of Phosphatidylserine
- May Improve Symptoms Alzheimer’s Disease
- Aids the Slowdown of Age-Related Cognitive Decline
- Combats Depression
- Improves Parkinson’s Disease Symptoms
- Treats ADHD Symptoms
- Boosts Athletic Performance
Safety and Side Effects
Phosphatidylserine is considered safe when taken by mouth in appropriate dosages. In studies, it has been used for up to six months.
Possible side effects of phosphatidylserine, especially at doses over 300 milligrams, include insomnia and upset stomach.
You should not take phosphatidylserine if you take any type of blood thinner. You should also use caution when combining it with natural blood-thinning supplements like ginkgo biloba. If you have a chronic medical condition or if you’re trying to conceive, pregnant, breast-feeding, under the age of 18 or taking other medications, speak with your doctor before taking PS.
What is Phosphatidyl Choline
Phosphatidylcholine (PC) is a phospholipid attached to a choline particle. Phospholipids contain fatty acids, glycerol, and phosphorous.
The phosphorous part of the phospholipid substance — the lecithin — is made up of PC. For this reason, the terms phosphatidylcholine and lecithin are often used interchangeably, although they’re different. Foods that contain lecithin are the best dietary sources of PC.
Although PC is traditionally used to support brain health, it can also support liver function and keep cholesterol levels in check. Read on to learn what the research says about the benefits of this nutritional supplement.
Phosphatidyl Choline Benefits
- Helps boost cognitive function
- May assist with Liver repair
- It may help protect against medication side effects
- It may help ease symptoms of ulcerative colitis
- It may help dissolve gallstones
Safety and Side Effects
Phosphatidylcholine is POSSIBLY SAFE when taken by mouth, when injected just beneath the skin, or when applied on the skin short-term. The safety of long-term use is not known.
When phosphatidylcholine is taken in excess by mouth, it can sometimes cause excessive sweating, stomach upset, and diarrhea.
Special Precautions & Warnings:
Phosphatidylcholine is POSSIBLY SAFE when taken by mouth Breast-feeding:
There is not enough reliable information about the safety of taking phosphatidylcholine when you are breastfeeding. Stay on the safe side and avoid use.
Serving size: 1 capsule
Servings per container: 60 capsules
As a food supplement, take 1 capsule daily with food, or as directed by your healthcare practitioner.
Age-related cognitive or memory impairment: 1 capsule 3 times a day
ADHD in children: 1 capsule 2 times a day
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