Top Nutritional Supplement Trends in 2025

As we step into 2025, the health and wellness industry continues to grow at a rapid pace, with nutritional supplements playing a key role in proactive self-care. From advanced delivery formats to personalised nutrition, supplement trends are becoming more refined, effective, and aligned with evolving consumer values. Here's a look at the top supplement trends shaping the industry this year, both globally and within the South African market.
1. Personalised Nutrition
Tailored health solutions are no longer a luxury—they're a growing expectation. Advances in DNA testing, microbiome analysis, and lifestyle tracking have opened doors to highly personalised supplement protocols. Consumers want products that fit their unique biology, not a one-size-fits-all approach.
2. Stress and Mood Support
As mental health remains a global concern, supplements targeting stress, anxiety, and sleep continue to soar. Ingredients like Ashwagandha, L-theanine, Lemon Balm, and Magnesium are being prioritised for their calming effects. In South Africa, there's growing demand for adaptogenic herbs and traditional African botanicals that support emotional well-being.

3. Immune Health—Still Going Strong
While the COVID-19 pandemic may be in the rear-view mirror, immunity remains a top concern. Products featuring Vitamin C, D3, Zinc, and medicinal mushrooms like Reishi and Lion’s Mane are still highly sought after. South African consumers are also looking for multi-functional immune boosters that double up for daily wellness.
4. Clean and Conscious Labels
Consumers want to know what they’re putting into their bodies. Clean-label supplements with no fillers, artificial colours, or preservatives are more appealing than ever. Vegan, gluten-free, palm-oil-free, and cruelty-free products are no longer niche—they’re mainstream expectations. In South Africa, this is particularly relevant among young professionals and millennial parents.

5. Gut Health and the Microbiome
The gut is the gateway to overall health, and 2025 sees no slowing down in probiotic and prebiotic interest. South Africans are embracing synbiotics, fermented supplements, and fibre-rich formulations to improve digestion, immunity, and even mental health. Look out for more advanced gut-focused blends, especially those combining digestive enzymes with herbs.
6. Innovative Delivery Systems
Traditional tablets are taking a back seat to more innovative, user-friendly formats like liquid drops, powders, sprays, gummies, and capsules with enhanced bioavailability. This is especially important in the local market where compliance and ease of use matter.

7. Longevity and Healthy Ageing
Supplements targeting cellular health, energy metabolism, and anti-inflammatory pathways are in demand, especially among Gen X and Boomers. Ingredients like NMN, resveratrol, and CoQ10 are trending, as are natural anti-ageing blends combining herbs, vitamins, and antioxidants.
8. Sports and Recovery
The South African supplement market is seeing a sharp rise in interest around muscle recovery, endurance, and performance—especially from amateur athletes and fitness enthusiasts. Magnesium, electrolytes, collagen, and clean protein powders are leading the pack.

9. Beauty-from-Within
Skin, hair, and nail supplements are on the rise, with collagen, hyaluronic acid, and biotin remaining at the forefront. Consumers want clinically tested beauty formulas that show real results without synthetic additives.
10. Local Ingredients and Sustainability
South African shoppers are embracing products that support local economies and sustainability. There’s growing interest in African botanicals like Moringa, Baobab, Buchu, and Devil’s Claw, as well as eco-friendly packaging and traceable sourcing practices.

By 2025, health-conscious consumers are looking for more than just trendy formulations—they want targeted, trusted, and effective supplements that genuinely support their well-being. South African shoppers are aligning with global trends, demanding personalised nutrition, clean ingredients, and clinically-backed results—but they're also becoming more discerning about where their supplements come from.
At Sfera Bio Nutrition, we’re listening and responding to what consumers want. We believe that taking care of yourself should be simple when you have the right support. That doesn’t always mean chasing the latest fad—it means finding a brand you trust to deliver high-quality, effective nutritional supplements.
We source only the finest ingredients from around the world and prepare our products locally in South Africa, with your wellness in mind. Sfera has always been at the forefront of health innovation, with our finger firmly on the pulse. We’re proud to offer the supplements that many others only catch onto later.
When it comes to better health, choose a brand that stays ahead—choose Sfera.
References:
- https://www.nutritionaloutlook.com/view/2025-vision-what-s-next-for-dietary-supplements
- https://www.euromonitor.com/article/top-10-global-consumer-trends-2025
- https://www.wellnesscreatives.com/supplement-industry-trends/
- https://www.spins.com/resources/2025-supplement-trends/
- https://www.mintel.com/