5-HTP Complex (Griffonia Seed Extract)

60 Capsules

R 482

Delivery in 2 - 3 working days

Sfera 5-HTP complex is a combination of Griffonia seed extract and Pyridoxal-5-Phosphate (cofactor vitamin B6) with the aim to help promote healthy mood balance and may be used as a sleep aid.

Griffonia simplicifolia, also known as griffonia, is a shrub native to West-Africa and Central-Africa. Seeds from the griffonia plant is used as a herbal remedy due to the seed’s high content of 5-Hydroxytryptophan (5-HTP). 5-HTP is an amino acid precursor to serotonin. 5-HTP may help to promote healthy mood balance and may be used a sleep aid. In Sfera products a Griffonia simplicifolia extract with a 5-HTP content of no less than 98% is used.

Pyridoxal-5-phosphate is a form of Vitamin B6 vitamin supplement. Vitamin B6 provides an array of health benefits and may assist with general wellbeing. In Sfera products a Pyridoxal-5-Phosphate with a purity of no less than 99% is used.  



One vegetarian capsule provides:


Griffonia simplicifolia (Griffonia) [seed, extract]

100 mg

(providing 98% L-5-hydroxytryptophan)


Pyridoxal-5-Phosphate (P-5-P)

20 mg

Other ingredients: Vegetarian capsule and microcrystalline cellulose.




Take one (1) to two (2) capsules per day after a meal, or as directed by your health care provider.

    Key Benefits

    • Sfera 5-HTP Complex helps to promote healthy mood balance and may be used as a sleep aid.


    Warnings & Precautions

    Do not take Sfera 5-HTP Complex:

    • if you are hypersensitive (allergic) to any of the ingredients of Sfera 5-HTP Complex.
    • if you have scleroderma (a chronic hardening and contraction of the skin and connective tissue, either locally or throughout the body).

    Warnings and precautions:

    Take special care with Sfera 5-HTP Complex  

    • avoid taking with alcohol or products that cause drowsiness.
    • if you show signs of weakness, oral ulcers, abdominal pain accompanied by severe muscle pain or if you experience skin changes.
    • if sleeplessness persists continuously for more than 4 weeks (chronic insomnia).


    Other medicines and Sfera 5-HTP Complex :

    Always tell your health care provider if you are taking any other medicine. (This includes all complementary or traditional medicines.)

    Consult a health care provider prior to use if you are taking carbidopa, or medicines/supplements with serotonergic activity.  These may include, but are not limited to, L-tryptophan, S-adenosylmethionine (SAMe), St. John’s wort, antidepressants, pain killers, over the counter cough and cold medicine containing dextromethorphan, anti-nausea medication and anti-migraine medication.

    Avoid taking with alcohol or products that cause drowsiness.

    Children and adolescents: Children and adolescents under the age of 18 years should not take Sfera 5-HTP Complex.

    Pregnancy and breastfeeding: If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, please consult your doctor, pharmacist or other health care provider for advice before taking this medicine.


    [1] SAHPRA Complementary Medicines – Health Supplements Safety and Efficacy

    [2] Sfera 5-HTP Complex Patient information leaflet

    [3] Canadian Monograph: 5-HTP

      Disclaimer: Product information and images correct at the time of publication. Sfera regularly updates product formulations and packaging to improve efficacy and quality, which can result in 2 or more concurrent variations in current stock in circulation.

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