5-HTP Complex (Griffonia Seed Extract)

60 Capsules

R 368

Delivery in 2 - 3 working days

Sfera 5-HTP complex is a combination of Griffonia seed extract and Pyridoxal-5-Phosphate (cofactor vitamin B6) with the aim to help promote healthy mood balance and may be used as a sleep aid.

Griffonia simplicifolia, also known as griffonia, is a shrub native to West-Africa and Central-Africa. Seeds from the griffonia plant is used as a herbal remedy due to the seed’s high content of 5-Hydroxytryptophan (5-HTP). 5-HTP is an amino acid precursor to serotonin. 5-HTP may help to promote healthy mood balance and may be used a sleep aid. In Sfera products a Griffonia simplicifolia extract with a 5-HTP content of no less than 98% is used.

Pyridoxal-5-phosphate is a form of Vitamin B6 vitamin supplement. Vitamin B6 provides an array of health benefits and may assist with general wellbeing. In Sfera products a Pyridoxal-5-Phosphate with a purity of no less than 99% is used.  



One vegetarian capsule provides:


Griffonia simplicifolia (Griffonia) [seed, extract]

100 mg

(providing 98% L-5-hydroxytryptophan)


Pyridoxal-5-Phosphate (P-5-P)

20 mg

Other ingredients: Vegetarian capsule and microcrystalline cellulose.




Take one (1) to two (2) capsules per day after a meal, or as directed by your health care provider.

    Dear Client

    At Sfera Bio Nutrition we are implementing some changes, which we would like to share with you. We are making label improvements and updates and are switching over to gold-coloured child-proof lids. These changes have been phased in over the last year and you may still encounter some of our stock with black lids, and previous label versions that are still in circulation during this time.

    If you have any questions, please do not hesitate to contact us.


    Key Benefits

    • Sfera 5-HTP Complex helps to promote healthy mood balance and may be used as a sleep aid.


    Warnings & Precautions

    Do not take Sfera 5-HTP Complex:

    • if you are hypersensitive (allergic) to any of the ingredients of Sfera 5-HTP Complex.
    • if you have scleroderma (a chronic hardening and contraction of the skin and connective tissue, either locally or throughout the body).

    Warnings and precautions:

    Take special care with Sfera 5-HTP Complex  

    • avoid taking with alcohol or products that cause drowsiness.
    • if you show signs of weakness, oral ulcers, abdominal pain accompanied by severe muscle pain or if you experience skin changes.
    • if sleeplessness persists continuously for more than 4 weeks (chronic insomnia).


    Other medicines and Sfera 5-HTP Complex :

    Always tell your health care provider if you are taking any other medicine. (This includes all complementary or traditional medicines.)

    Consult a health care provider prior to use if you are taking carbidopa, or medicines/supplements with serotonergic activity.  These may include, but are not limited to, L-tryptophan, S-adenosylmethionine (SAMe), St. John’s wort, antidepressants, pain killers, over the counter cough and cold medicine containing dextromethorphan, anti-nausea medication and anti-migraine medication.

    Avoid taking with alcohol or products that cause drowsiness.

    Children and adolescents: Children and adolescents under the age of 18 years should not take Sfera 5-HTP Complex.

    Pregnancy and breastfeeding: If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, please consult your doctor, pharmacist or other health care provider for advice before taking this medicine.


    [1] SAHPRA Complementary Medicines – Health Supplements Safety and Efficacy

    [2] Sfera 5-HTP Complex Patient information leaflet

    [3] Canadian Monograph: 5-HTP